Fascinating interview. To avoid the 2.5 hour listen, this summary from a commenter on YouTube sums it up well:
T_he result of this conversation is that you should think really hard about your next ai business idea. Don't just rush off and make a wrapper, but try to create a product that will use the ai tools we have today on a new level - know the steps of your user beforehand and make your product go through them instead of the user. The user saves time in the process. Now, what's the next step of improvement? do that! What's the third step? do that!_